Arithmetic progression of prot P31946 (1433B_HUMAN)
14-3-3 protein beta/alpha
The results of our research show that the processes of sequencing the molecules are conditioned and arranged not only with chemical and biochemical lawfulness, but also with program, cybernetic and informational lawfulness too. At the first stage of our research we replaced nucleotides from the Amino Acid Code Matrix with numbers of the atoms in those nucleotides. Translation of the biochemical language of these amino acids into a digital language may be very useful for developing new methods of predicting protein sub-cellular localization, membrane protein type, or any other protein attributes. Since the concept of Chou's pseudo amino acid composition was proposed 1,2, there have been many efforts to try to use various digital numbers to represent the 20 native amino acids in order to better reflect the sequence-order effects through the vehicle of pseudo amino acid composition. Some investigators used complexity measure factor 3, some used the values derived from the cellular automata 4-7, some used hydrophobic and/or hydrophilic values 8-16, some were through Fourier transform 17,18, and some used the physicochemical distance 19. It is going to be possible to use a completely new strategy of research in genetics in the future. However, close observation of all these relationships, which are the outcomes of periodic laws (more specifically the law of binary coding), stereo-chemical and digital structure of proteins.
The author reports no conflict of interest in this research.
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