utorak, 19. listopada 2010.

Correlation of the methylation of BRCA1 and RASSF1A in EOC tissues (5)

Classical and information parameters of the methylation of BRCA1 and RASSF1A in EOC tissues

The subject of the research we are discussing in this text is the cyber-information access to the research of the DNA constitution of the methylation of BRCA1 and RASSF1A in EOC tissues. Strictly speaking, the subject of this research is finding of an adequate scientific language that could describe this phenomenon, study of the genetic information, as well as relationship between the genetic language of the protein and the theory of the system and cybernetics. By using the system and information procedures and methods in studying biochemistry, we can analyze the effects of the classical and information parameters of the methylation of BRCA1 and RASSF1A in EOC tissues. Examples:


Bio code 400

R5-BRCA1(u)3’ = 400

R4-RASSF1A(m)3’ = (-)400

R3-BRCA1(u)3’ = (-)400

R3-BRCA1(m)3’ = (-)400

R4-RASSF1A(m)3’ = (-)400

R16-RASSF1A(u)3’ = (-)400

Bio code 1188

R3-BRCA(unmethylation)3’ = 1188

R7-RASSF1A(unmethylation)3’=1188

R19 RASSF1A(unmethylation)3’ = 1188

R18 RASSF1A(unmethylation)5’ =1188

Bio code (-)1192

R14-BRCA1(u)5’ = (-)1192

R16-BRCA1(u)3’= (-)1192

Bio code 1200

R1-BRCA1(u)3’ = 1200

R1-RASSF1A (methylation)3’ = 1200

R3-RASSF1A(unmethylation)3’ = 1200

R4-RASSF1A(u)3’ = 1200

R2-RASSF1A(u)3’ = (-)1200

R6-RASSF1A(u)3’ = (-)1200

Bio code (-)39996

R17-RASSF1A(u)3’ = (-)39996

R4-BRCA1(u)3’ = (-)39996

R4-BRCA1(m)3’ = (-)39996


Bio code (-)40000

R6-BRCA1(u)3’ = 40000

R6-BRCA1(m)3’ = 40000

R13-RASSF1A (methylation)3’ = (-)40000

R15-RASSF1A (unmethylation)3’ = (-)40000

Bio code (-)40792

R7-BRCA1(u)5’ = (-)40792

R9-BRCA1(u)3’ = (-)40792

R9-BRCA1(m)3’ = (-)40792

R7-BRCA1(m)5’ = (-)40792

Bio code 78800

R1-BRCA(unmethylation)3’ = 78800

R1-BRCA(methylation)3’= 78800

R12-BRCA1(u)3’ = (-)78800

R12-BRCA1(m)3’ = (-)78800

Bio code 79208

R18-BRCA1(u)3’ = 79208

R20-BRCA1(m)3’ = 79208

R18-BRCA1(m)3’= 79208

R20-BRCA1(u)3’ = 79208

R10-BRCA1(u)3’ = (-)79208

R10-BRCA1(m)3’ = (-)79208

R19-BRCA1(u)3’ = (-)79208

R19-BRCA1(m)3’ = (-)79208

Bio code 79212

R11-BRCA1(u)3’ = 79212

R9-RASSF1A(u)3’ = 79212

R11-BRCA1(m)3’ = 79212

R9-BRCA(unmethylation)3’ = (-)79212

R9-BRCA(methylation)3’ = (-)79212

Bio code (-)119208

R15-BRCA1(u)5’ = (-)119208

R17-BRCA1(u)3’ = (-)119208

Bio code 119996

R3-RASSF1A(m)3’ = (+)119996

R15-RASSF1A(u)3’ = (+)119996

R2-BRCA1(u)3’ = (+)119996

R2-BRCA1(m)3’ = (+)119996

R20-BRCA(unmethylation)3’ = (-)119996

R20-BRCA(methylation)3’ = (-)119996

Bio code 119988

R14-BRCA(unmethylation)3’= 119988

R5-RASSF1A(u)3’ = 119988

R11-RASSF1A(m)3’ = 119988

R2-BRCA(unmethylation)3’= (-)119988

R2-BRCA(methylation)3’ = (-)119988

R1-RASSF1A(u)5’ = (-)119988

Bio code 120000

R13-BRCA1(u)3’ = 120000

R2-RASSF1A (methylation)3’ = 120000

R13-BRCA1(m)3’ = 120000

R4-RASSF1A (unmethylation)3’ = 120000

R5-BRCA(unmethylation)3’ = -120000

R1-RASSF1A(unmethylation)3’ = -120000

R10-RASSF1A (unmethylation)3’ = -120000

Bio code (-)198020

R16-BRCA(methylation)3’= (-)198020

R8-RASSF1A(m)3’ = (-)198020

R6-RASSF1A (methylation)3’ = (-)198020

R4-RASSF1A (methylation)5’ = (-)198020

Bio code 11920788

R7-BRCA(methylation)5’ = 11920788

R7-BRCA(unmethylation)5’ = 11920788

Bio code 12000000

R3-RASSF1A(unmethylation)5’ = 12000000

R1-RASSF1A(methylation)5’ = 12000000

Bio code 788118812

R10-BRCA(unmethylation)5’= (+)788118812

R10-RASSF1A(u)5’ = (-)788118812

Bio code 1188000012

R9-RASSF1A (unmethylation)5’ = 1188000012

R4-BRCA(unmethylation)5’ = 1188000012

Bio code 1192078812

R8-BRCA(methylation)5’ = 1192078812

R8-BRCA (unmethylation)5’ = 1192078812

Bio code 1980198800

R17 BRCA(methylation)5’ = 1980198800

R8-RASSF1A(m)5’ -1980198800

Bio code (-)1188118800

R11-BRCA(unmethylation)5’(-)1188118800

R12-RASSF1A(u)5’ (-)1188118800

Bio code (-)1991998808

R8-RASSF1A(methylation)5’ (-)1991998808

R5-BRCA(methylation)5’ (-)1991998808

Bio code (-)1199998808

R5-BRCA(unmethylation)5’ = (-)1199998808

R10-RASSF1A (unmethylation)5’= (-)1199998808

R11-RASSF1A (unmethylation)5’ = (-)1199998808

Figure 4. Bio codes of BRCA1 and RASSF1A in EOC tissues

Notes: The result of the research that we have carried out clearly shows that there is a matrix code of BRCA1 and RASSF1A in EOC tissues. It also shows that the coding system within the nucleotides language gives a full information, not only for the amino acid „record“, but also for its structure, configuration and its various shapes.

The digital language of biochemistry has a countless number of codes and analogue codes, as well as other information content. These pictures enable us to realize the very essence of functioning of biochemical processes.


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