Correlation of the methylation of BRCA1 and RASSF1A in EOC tissues (2)

ATOMIC NUMBERS

BRCA₁ unmethylation

G	G	T	T	A	A	T	T	T	A	G	A
78	78	66	66	70	70	66	66	66	70	78	70
1	2	3	4	5	6	7	8	9	10	11	12

G	T	T	T	T	G	A	G	A	G	A	T	G
78	66	66	66	66	78	70	78	70	78	70	66	78
13	14	15	16	17	18	19	20	21	22	23	24	25

T	C	A	A	C	A	A	A	C	T	C	A
66	58	70	70	58	70	70	70	58	66	58	70
1	2	3	4	5	6	7	8	9	10	11	12

C	A	C	C	A	C	A	C	A	A	T	C	A
58	70	58	58	70	58	70	58	70	70	66	58	70
13	14	15	16	17	18	19	20	21	22	23	24	25

BRCA₁ methylation

G	G	T	T	A	A	T	T	T	A	G	A	G
78	78	66	66	70	70	66	66	66	70	78	70	78
1	2	3	4	5	6	7	8	9	10	11	12	13

T	T	T	C	G	A	G	A	G	A	C	G
66	66	66	58	78	70	78	70	78	70	58	78
14	15	16	17	18	19	20	21	22	23	24	25

T	C	A	A	C	G	A	A	C	T	C	A
66	58	70	70	58	78	70	70	58	66	58	70
1	2	3	4	5	6	7	8	9	10	11	12

C	G	C	C	G	C	G	C	A	A	T	C	G
58	78	58	58	78	58	78	58	70	70	66	58	78
13	14	15	16	17	18	19	20	21	22	23	24	25

RASSF1A _, unmethylation

T	T	T	G	G	T	T	G	G	A	G	T
66	66	66	78	78	66	66	78	78	70	78	66
1	2	3	4	5	6	7	8	9	10	11	12

G	T	G	T	T	A	A	T	G	T	G
78	66	78	66	66	70	70	66	78	66	78
13	14	15	16	17	18	19	20	21	22	23

C	A	A	A	C	C	C	C	A	C	A	A
58	70	70	70	58	58	58	58	70	58	70	70
1	2	3	4	5	6	7	8	9	10	11	12

A	C	T	A	A	A	A	A	C	A	A
70	58	66	70	70	70	70	70	58	70	70
13	14	15	16	17	18	19	20	21	22	23

RASSF1A methylation

G	T	G	T	T	A	A	C	G	C
78	66	78	66	66	70	70	58	78	58
1	2	3	4	5	6	7	8	9	10

G	T	T	G	C	G	T	A	T	C
78	66	66	78	58	78	66	70	66	58
11	12	13	14	15	16	17	18	19	20

A	A	C	C	C	C	G	C	G	A
70	70	58	58	58	58	78	58	78	70
1	2	3	4	5	6	7	8	9	10

A	C	T	A	A	A	A	A	C	G	A
70	58	66	70	70	70	70	70	58	78	70
11	12	13	14	15	16	17	18	19	20	21

Figure 1. Atomic numbers in primer sequences

Notes: And in that dimension we can find an explanation for the given empirical reality. Aforementioned nucleotides are positioned from number 1 to 25,23 and 20. Numbers 1, 2, 3, n... present the position of a certain nucleotide.